The Second Generation PRP

Orogen Plus (PRP with a “protein matrix”)

What is the importance of a “matrix”? Think of a matrix as a “scaffold”. The scaffold entraps growth factors allowing the healing capable cells to multiply and remold the area of injury.
Figure 1(above left) is an electron microscope image of the matrix while Figure 2(above right) is a view deep inside the matrix illustrating how the protein entraps the growth factors. Since it takes the body longer to break down protein, the growth factors and healing capable cells remain over the treatment area longer allowing more new cells to attach promoting healing.

Independent studies conclude that, “GF–ECM complexes may well be the most effective and efficient method to stimulate cell proliferation, as well as tissue healing or regeneration”.

1-Clark, R et al. Synergistic Signaling from Extra cellular Matrix–Growth Factor Complexes. Journal of Investigative Dermatology (2008) 128, 1354–1355. doi:10.1038/jid.2008.75